Eternal Sacred King - Chapter 3327 - : Human Saint

A Di [legitimate-born] daughter of a noble house turns into an abandoned daughter. No father to dote on her, no mother to love her, no problem. She uses one silver needle to save a dying man. What’s so unusual about a medical injection? She roams all over the world with a scalpel in her hand. Cutting throats, cutting open abdomens, cutting open skulls to mend bones. With amazing medical skills and ethics, she gathers a flock of officials, obtains the will of heavens, gains public favor, and receives Taizi’s [Crown Prince] doting. In the midst of a powerful momentum, her cheap father comes to reunite. She coldly refuses to go home or acknowledge ancestors.

“I was abandoned by you over and over again. Now you want to use familial affection to coax me back. You don’t want to recognize this daughter. My heart is cold, I want to leave. Beat it, father!”

- Description from Novelupdates

This is an Isekai styled story, written from the point of view of the protagonist.

Discover the secret of the new, unknown world with Peter, as he sets his first steps in an empty, ruined city. Meet new people from all around the globe. Fight, laugh, and cry.

Huang Dan’s pain nerve is innately different from the ordinary people. A little tore in his skin can cause him to sweat all over his body painfully to the point of him unable to make a word out.

Somehow, he began to cross world, following Mr. System to do the tasks…

In the first world, Huang Dan realizes what it means to die painfully and to live to die again.

TL’s summary:
MC suddenly transmigrated and is bind to a system, requiring him to solve mysteries. Born with a higher degree of pain sensitivity, he met different people in the different worlds and learns what kind of emotion smiling is.

- Description from Novelupdates

16 years old-- most boys would be falling in love, as their hormones all rise to unprecedented levels. Most boys at Riley's age would have dreams; dreams that will slowly grow into passion. Riley, however, at age 16... killed the world's number 1 superhero.