MTL - The Strongest System - Chapter 1158 This is impossible

Ji Yan discovered his wife, who hated him so much that she wished he was dead, had lost her memory after a car crash. She had changed so much it was like she was a totally different person…

Utsuro no Hako to Zero no Maria, or The Empty Box and The Zeroth Maria, tells the sinister story of Kazuki Hoshino, who is almost madly attached to his everyday life, and his antagonist Aya Otonashi, who suddenly transfers into his class—for the 13,118th time. She majestically announces to “break” him, without paying heed to anyone else around them.

The world that nurtured the civilization which reached the pinnacle of magic was on the verge of destruction.
The last survivor transmigrated to the past, when the magic civilization started growing, as countless mages were still fumbling their ways through the thorny paths of magic knowledge.
He, who came from the end of the magic era, aim to reach the pinnacle of magic.

- Description from Novelupdates

She was the head of a powerful, medicine-orientated aristocratic family.

Crossing through a millennium, she ended up in the body of the General Household’s “trash” young miss, whose engagement with the Crown Prince was just broken as she suffered under everybody’s taunts!

In the drafting feast, she was re-engaged by the Emperor to marry the famous disabled prince!

Everybody laughed, a blind trash with a disabled wastrel. What a perfect match!

However, they didn’t know that in her hand, she grasped the long-lost primordial pill recipes! Her practice in medicine had reached the apex! Her contracted beasts were unique in the world!

What was the most frightening, was the disabled prince she was engaged to…….

A black-belly full of dirty tricks, with a heaven-opposing cultivation physique, he defeats all geniuses!

In his wheelchair during the day, yet entangling her in bed as he trained his waist muscles… MF! Is he really crippled!?

- Description from Novelupdates