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Chapter 79: Grief
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Chapter 81: Different Effects
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... loped by Orochimaru had shown a peculiar limitation—though it was remarkably effective, it could only be used twice within a year. After the second use, any subsequent dose would see drastically diminished effects. This wasn't exactly a "drawback," but it was certainly a limitation. Hiruzen had hoped that Orochimaru would eventually overcome it, but at the time, Orochimaru mentioned he was working on something new and more powerful. With other pressing matters at hand, Hiruzen had refrained from ...
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