Surgery Godfather-Chapter 1843 - 1290: Different Meanings

The convoy arrived at Sanbo Hospital, and Li Gaoyang was quickly transferred to the Intensive Care Unit of the Institute, as he was currently in life-threatening condition.

"Professor Yang, may I observe the entire treatment process? Not officially, but as a personal learning opportunity?" John Ansen requested, having long considered himself one of Yang Ping’s students, and he was one of the founding members of Yang Ping’s online academic forum and WeChat group.

"Of course!" Yang Ping nodded.

John Ansen was quite excited: "Thank you." He appreciated Yang Ping not looking down on him despite the arrogance of the United States.

Yang Ping said, "Now we first need to perform external ventricular drainage for Li Gaoyang, you can come in and have a look."

The surgery started half an hour later, with Song Zimo as the chief surgeon. The puncture needle precisely entered the lateral ventricle, and dark red cerebrospinal fluid flowed out, causing the intracranial pressure monitor’s values to quickly decrease.

The entire surgery only took ten minutes.

"God..." John Ansen murmured, "Dr. Song is already this proficient at surgery."

Although external ventricular drainage is a minor procedure, it still showcases the doctor’s professional ethics.

After not seeing each other for a while, John Ansen didn’t expect Song Zimo to have improved so much, and while he praised her, he couldn’t help but feel a bit ashamed inside.

Twenty-four hours after the drainage procedure, Li Gaoyang’s symptoms alleviated somewhat.

Rolf was sitting by the bed in isolation attire, holding Li Gaoyang’s hand. "Professor Yang said that tomorrow will start the first phase of treatment, using the world’s most advanced K therapy. You almost missed out on this new method; it’s all your own doing, but luckily, you realized the truth at the critical moment and made the right choice."

Li Gaoyang nodded, indicating his understanding.

"Also..." Rolf lowered his voice, "The people from the White House and the FDA have been pressing for data, and luckily, Professor Yang doesn’t mind sharing your treatment data with them..."

Li Gaoyang’s hand slightly tightened its grip on Rolf’s hand: "Living... is having everything..."

The next day at 9 a.m., the treatment officially began.

The principle of K therapy is not actually complex. It involves administering adeno-associated viral vectors carrying therapeutic genes through intravenous injection into the blood, with the blood circulation carrying them throughout the body, including penetrating the blood-brain barrier, infecting tumor cells, and triggering the tumor cells’ apoptosis program, thus causing tumor cell death. This infection and triggering has a high selectivity.

In the treatment room, the atmosphere was relaxed.

Yang Ping stood beside, the nurse operated the medication, Song Zimo monitored the vital signs, Xu Zhiliang recorded the data, John Ansen observed, and a large group of graduate students were gathered around.

John Ansen was very surprised that the world’s top tumor treatment method was so simple, resembling regular infusions, requiring neither expensive specialized treatment rooms nor complex operational techniques, not even sterile isolation attire.

"Start administering medication." The nurse opened the infusion set switch. 𝚏𝕣𝐞𝗲𝐰𝕖𝐛𝐧𝕠𝕧𝚎𝚕.𝐜𝚘𝗺

"No need to be so nervous, it’s actually just an infusion." Yang Ping comforted the trembling Li Gaoyang. His family’s considerable efforts had secured this opportunity for him.

"The patient’s vital signs are stable," Song Zimo said.

The infusion lasted forty minutes, after which Li Gaoyang was sent to the Intensive Care Unit for a 48-hour intensive monitoring to observe immune response and early efficacy.

On the first day, nothing happened.

On the afternoon of the second day, Li Gaoyang’s temperature began to rise, reaching 38.5 degrees Celsius.

"Immune activation response." Yang Ping looked at the data, "A normal reaction, meaning the viral vectors are working."

But by evening, the temperature rose to 39.8 degrees, with an accelerated heart rate and fluctuating blood pressure.

"Isn’t it too intense?" Song Zimo inquired, "Does it need to be handled?"

John Ansen nervously waited for Yang Ping’s response nearby.

"Continue to observe," Yang Ping said, "Unless there is organ function damage, we do not intervene in the immune process. Multiple clinical trials tell us it is safe and controllable, although accidents cannot be ruled out."

The intense immune response is the most dangerous part of the first-generation K therapy—an overly intense activated immune system can harm normal tissues.

Sisi almost lost her life due to such an intense immune response, but after several iterations, this response is now entirely within a controllable range. However, due to ethnic differences, Li Gaoyang’s reaction was still slightly intense.

At 2 a.m., Li Gaoyang’s temperature broke 40 degrees, and he began to experience convulsions. For safety, the doctors sedated him and put him on a ventilator for assisted breathing.

"Brain edema is worsening," Song Zimo stared at the monitoring images, "The tumor area shows a significant inflammatory response."

Everyone held their breath, Rolf paced anxiously in the observation room, while John Ansen rapidly took notes, witnessing a treatment reaction model he had never seen before.

Yang Ping seemed very relaxed and ordered: "Administer a methylprednisolone shock, control cerebral edema, and start cooling treatment."

"No need to be overly tense. We just need symptomatic treatment." Yang Ping reassured John Ansen beside him.

Medication was administered, physical cooling started. The next six hours were a long wait. Li Gaoyang struggled on the brink of life and death, while the medical team recorded data every ten minutes and adjusted the plan.

Li Gaoyang’s timing for treatment wasn’t great, with significant cerebral edema already present, coupled with ethnic differences, the side effect was still slightly intense.

As the morning sunlight filtered through the blinds into the intensive care unit, Li Gaoyang’s temperature finally began to drop. 39 degrees... 38.5 degrees... 38 degrees. Convulsions ceased, and parameters improved.